APC anti-human CD213a2 IL13Ralpha2 Antibody anti-CD213a2 - SHM38,BioLegend,354406
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB777728564
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAPC anti-human CD213a2 IL13Ralpha2 Antibody anti-CD213a2 - SHM38
Cat. No.354406
HostMouse
RRIDAB_2562582 (BioLegend Cat. No. 354405)AB_2562583 (BioLegend Cat. No. 354406)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberSHM38
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD213a2
ImmunogenMelanoma cell line A375
PurityThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD213a2, also known as IL-13Rα2, is a type I transmembrane protein and member of the hematopoietin family. IL13Ra2 is the high affinity receptor for IL-13, but it possibly acts as a decoy receptor to antagonize IL-13Rα1/IL-4Ra-mediated IL-13 biological functions. IL13Rα2 is expressed by fibroblasts, smooth muscle cells, keratinocytes and activated B cells. However, its presence on the cell surface is highly regulated. CD213a2 is also expressed in various types of cancer which makes it an attractive therapeutic target.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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