APC anti-human CD217 Antibody anti-CD217 - W15177A,BioLegend,372306

Host

Mouse

Reactivity

Human

Application

FC - Quality tested

Platform ID

BAB953266794

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

BioLegend

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameAPC anti-human CD217 Antibody anti-CD217 - W15177A
Cat. No.372306
HostMouse
RRIDAB_2632913 (BioLegend Cat. No. 372305)AB_2632914 (BioLegend Cat. No. 372306)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberW15177A
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD217
ImmunogenP3U1 cells stably transfected with CD217.
PurityThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

Six interleukin-17 (IL-17)-family (IL-17A-IL-17F) and five IL-17 receptor (IL-17R)-family (IL-17RA-IL-17RE) members have been reported in mammalian cells. IL-17RA (known as IL-17R, IL-17AR, CD217) is a 128-158 kD type I transmembrane glycoprotein. IL-17R binds to IL-17A (also known as IL-17, and CTLA-8, is a hallmarker of Th17 cells) and IL-17F and mediates the proinflammatory signals through interaction with IL-17RC or IL-17RD. IL-17R has broad tissue distribution, including fibroblasts, epithelial cells, endothelial cells, stromal cells, B cells, T cells, NK cells, monocytes and granulocytes.

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.