APC anti-human CD27 Antibody, CD27, S20020H,BioLegend,385008
Clone S20020H does not block binding of clones M-T271, O323, or S20020G on target cells.Clone S20020H can block binding between CD27 and CD70 (CD27L).
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB511000333
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameAPC anti-human CD27 Antibody, CD27, S20020H
Cat. No.385008
HostMouse
RRIDAB_3083387 (BioLegend Cat. No. 385007)AB_3083387 (BioLegend Cat. No. 385008)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberS20020H
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD27
ImmunogenHu CD27 transfected cells
PurityThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70 and plays an important role in costimulation of T cell activation, and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-κB and SAPK/JNK activation.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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