APC anti-human CD285 (TLR5) Antibody, CD285, S16021I,BioLegend,394508
Host
Mouse
Reactivity
Human
Application
FC -Quality tested
Platform ID
BAB004953237
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAPC anti-human CD285 (TLR5) Antibody, CD285, S16021I
Cat. No.394508
HostMouse
RRIDAB_2832760 (BioLegend Cat. No. 394507)AB_2832761 (BioLegend Cat. No. 394508)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone NumberS16021I
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD285
ImmunogenHuman TLR5 transfectants
PurityThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD285, also known as TLR5, is a 98 kD pattern recognition receptor that binds to bacterial flagellin. It is expressed on dendritic cells, classical monocytes and mucosal epithelial cells and is involved in activation of TLR5 induced NF-κB mediated activation of inflammatory-related target genes. Mutations in the TLR5 gene have been linked with susceptibility to systemic lupus erythematosus and Legionnaire’s disease.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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