APC anti-human CD7 Antibody anti-CD7 - CD7-6B7,BioLegend,343108
Additional reported (for the relevant formats) applications include proteogenomics2.
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB028364523
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
Email:
Product Specifications
Scientific Background
Specifications
NameAPC anti-human CD7 Antibody anti-CD7 - CD7-6B7
Cat. No.343108
HostMouse
RRIDAB_1877156 (BioLegend Cat. No. 343107)AB_2291325 (BioLegend Cat. No. 343108)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberCD7-6B7
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD7
ImmunogenKG1a cell line
PurityThe antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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