APC anti-human HLA-DR, DP, DQ Antibody Tü39,BioLegend,361714
Tü39 has been reported to react with a shared epitope of HLA-DR, HLA-DP, and HLA-DQ.Additional reported applications (of relevant formats) include immunoprecipitation6,in vitroblocking of MLR5, and suppressor cell generation4. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (contact our custom solutions team).
Host
Mouse
Reactivity
Human
Application
FC -Quality tested
Platform ID
BAB223093537
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
Email:
Product Specifications
Scientific Background
Specifications
NameAPC anti-human HLA-DR, DP, DQ Antibody Tü39
Cat. No.361714
HostMouse
RRIDAB_2750315 (BioLegend Cat. No. 361713)AB_2750316 (BioLegend Cat. No. 361714)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone NumberTü39
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetHLA-DR DP DQ
ImmunogenHuman PBL
PurityThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
HLA-DR, HLA-DP, and HLA-DQ are heterodimeric cell surface glycoproteins comprised of an α (heavy) chain and a β (light) chain. They are expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. Variations in the HLA gene expression are crucial to graft survival.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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