APC anti-human LGR5 (GPR49) Antibody, LGR5 (GPR49) , SA222C5,BioLegend,373805
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB763624073
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAPC anti-human LGR5 (GPR49) Antibody, LGR5 (GPR49) , SA222C5
Cat. No.373805
HostMouse
RRIDAB_2904406 (BioLegend Cat. No. 373805)AB_2904406 (BioLegend Cat. No. 373806)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberSA222C5
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetLGR5
ImmunogenHuman LGR5 transfectant cells
PurityThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
LGR5, also known as GPR49, is a 100 KD protein. It is a member of GPCR class A orphan receptor proteins which binds R-spondin and does not activate through heterotrimeric G protein like other GPCR. It triggers the Wnt signaling pathway downstream. LGR5 is expressed across a diverse range of tissue such as in the muscle, placenta, spinal cord and brain and particularly as a biomarker of adult stem cells in certain tissues.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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