APC anti-human TSPAN33 (BAAM) Antibody, TSPAN33, SA17RN1,BioLegend,395405

Host

Mouse

Reactivity

Human

Application

FC -Quality tested

Platform ID

BAB200593078

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameAPC anti-human TSPAN33 (BAAM) Antibody, TSPAN33, SA17RN1
Cat. No.395405
HostMouse
RRIDAB_2801043 (BioLegend Cat. No. 395405)AB_2801044 (BioLegend Cat. No. 395406)
IsotypeMouse IgG2b, κ
ReactivityHuman
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone NumberSA17RN1
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetTSPAN33
ImmunogenHuman TSPAN33-transfected cells
PurityThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

TSPAN33, also known as BAAM, is a 32 kDa protein member of the TM4 superfamily (TM4SF). TSPAN33 have four transmembrane regions and two extracellular loops, one of them is a cysteine-rich long extracellular loop (LEL), characteristic of the TM4SF. TSPAN33 interacts with different molecules such as integrins and other tetraspanins. TSPAN33 is expressed by activated B cells, some B cell lymphomas, macrophages and in cells from the convoluted tubules and collecting ducts in the kidney. In macrophages TSPAN33 modulates TLR-induced proinflammatory gene expression, but its function in other cells is unknown.

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