APC anti-mouse AhR Antibody, AhR, W16012C,BioLegend,162705
Host
Rat
Reactivity
Mouse
Application
ICFC - Quality tested
Platform ID
BAB640960451
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameAPC anti-mouse AhR Antibody, AhR, W16012C
Cat. No.162705
HostRat
RRIDAB_3720526 (BioLegend Cat. No. 162705)AB_3720526 (BioLegend Cat. No. 162706)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationICFC - Quality tested
ClonalityMonoclonal
Clone NumberW16012C
Concentration0.2 mg/mL
TargetAhR
PurityThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
The aryl hydrocarbon receptor (AhR) is a basic helix-loop-helix transcription factor that is activated by multiple ligands such as TCDD. It is expressed in many immune cells and performs an important role in immune regulation. AhR is induced under Th17-polarizing conditions. In its inactive state, AhR is present in the cytoplasm, but upon ligand binding, it translocates to the nucleus. Activation of AhR is tightly controlled by ubiquitination, ligand metabolism, and AhR complex disruption.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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