APC anti-mouse CD11a/CD18 LFA-1 Antibody anti-CD11a/CD18 - H155-78,BioLegend,141009

This clone is reported to have some effect on increasing LFA-1-mediated adhesion and does not block LFA-1 binding1.

Host

Rat

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB164421713

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameAPC anti-mouse CD11a/CD18 LFA-1 Antibody anti-CD11a/CD18 - H155-78
Cat. No.141009
HostRat
RRIDAB_2564305 (BioLegend Cat. No. 141009)AB_2564306 (BioLegend Cat. No. 141010)
IsotypeRat IgG1, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberH155-78
Concentration0.2 mg/ml
TargetCD11a or CD18
ImmunogenTH-derived anti-I-AkCTL clone A1 5.1.17
PurityThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

Lymphocyte function-associated antigen 1 or LFA-1 is a heterodimer composed of two members of the integrin family, αL(CD11a) and β2 (CD18).  LFA-1 is expressed primarily on lymphocytes, monocytes/macrophages, and granulocytes.  It is involved in cell adhesion and costimulation processes. The ligands for LFA-1 are ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

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