APC anti-mouse CD11c Antibody anti-CD11c - N418,BioLegend,117309
Additional reported applications (for the relevant formats) include: immunoprecipitation3, immunohistochemical staining of acetone-fixed frozen sections3, immunofluorescence microscopy5, 9(Alexa Fluor® 488 conjugated N418 was used for IHC in frozen sections10), and spatial biology (IBEX)22,23.
Host
Armenian Hamster
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB821218943
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameAPC anti-mouse CD11c Antibody anti-CD11c - N418
Cat. No.117309
HostArmenian Hamster
RRIDAB_313778 (BioLegend Cat. No. 117309)AB_313779 (BioLegend Cat. No. 117310)
IsotypeArmenian Hamster IgG
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberN418
Concentration0.2 mg/ml
TargetCD11c
ImmunogenMouse spleen dendritic cells
PurityThe antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe CD11c antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD11c is a 150 kD glycoprotein also known as αXintegrin, CR4, and p150. CD11c forms a αXβ2heterodimer with β2integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen, and CD54.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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