APC anti-mouse CD160 Antibody anti-CD160 - 7H1,BioLegend,143011

Host

Rat

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB009873403

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameAPC anti-mouse CD160 Antibody anti-CD160 - 7H1
Cat. No.143011
HostRat
RRIDAB_2562698 (BioLegend Cat. No. 143011)AB_2562699 (BioLegend Cat. No. 143012)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number7H1
Concentration0.2 mg/ml
TargetCD160
ImmunogenSoluble His-Tag mouse CD160
PurityThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD160, also known as BY55, is a 27 kD glycoprotein and member of the Ig superfamily. It is anchored to the cell membrane through glycosylphosphatidylinositol (GPI) and forms disulfide-linked multimers. A soluble form of CD160 is secreted by activated CD8+T cells. Expressed by NK, NKT, γ/δ T cells, intestinal intraepithelial T cells and a subset of memory CD8+T cells, CD160 binds both classical and non-classical MHC class I molecules. It is also a ligand for HVEM. CD160 enhances proliferation of activated CD8+T cells and triggers cell cytotoxicity in NK cells.

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