APC anti-mouse CD2 Antibody anti-CD2 - RM2-5,BioLegend,100112
Additional reported applications (for the relevant formats) include:in vitroblocking of CD2-mediated cell-cell adhesion and inhibition of T cell activation1, blocking of T cell A.I.C.D.2, immunoprecipitation3, and co-induction of thymocyte maturation4. The RM2-5 antibody can block CD2-mediated cell-cell adhesion. The Ultra-LEAF™ Purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos.100118 and 100119).
Host
Rat
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB397843410
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameAPC anti-mouse CD2 Antibody anti-CD2 - RM2-5
Cat. No.100112
HostRat
RRIDAB_2563089 (BioLegend Cat. No. 100111)AB_2563090 (BioLegend Cat. No. 100112)
IsotypeRat IgG2b, λ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberRM2-5
Concentration0.2 mg/ml
TargetCD2
ImmunogenBALB/c mouse thymocytes
PurityThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD2 is a 45-58 kD type I transmembrane glycoprotein, also known as LFA-2, T11 or Ly-37. It is a member of the Ig superfamily. Mouse CD2 is primarily expressed on T cells, B cells, thymocytes and NK cells. It is a ligand for CD48 and is involved in T cell activation and differentiation.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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