APC anti-mouse CD285 (TLR5) Antibody, CD285, ACT5,BioLegend,148105
Additional reported applications for the relevant formats include: immunoprecipitation of TLR5 from cell lysates1,2.
Host
Mouse
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB766245343
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAPC anti-mouse CD285 (TLR5) Antibody, CD285, ACT5
Cat. No.148105
HostMouse
RRIDAB_2890695 (BioLegend Cat. No. 148105)AB_2890695 (BioLegend Cat. No. 148106)
IsotypeMouse IgG1, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberACT5
Concentration0.2 mg/mL
TargetCD285
ImmunogenTLR5-transfected Ba/F3 cells
PurityThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD285, also known as TLR5, is a 98 kD pattern recognition receptor that binds to bacterial flagellin. It is expressed on dendritic cells, classical monocytes and mucosal epithelial cells and is involved in activation of TLR5 induced NF-κB mediated activation of inflammatory-related target genes. Mutations in the TLR5 gene have been linked with susceptibility to systemic lupus erythematosus and Legionnaire’s disease.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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