APC anti-mouse CD33 Antibody, CD33, W18124D,BioLegend,104805

Host

Rat

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB143909035

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameAPC anti-mouse CD33 Antibody, CD33, W18124D
Cat. No.104805
HostRat
RRIDAB_2927955 (BioLegend Cat. No. 104805)AB_2927955 (BioLegend Cat. No. 104806)
IsotypeRat IgG2a, λ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberW18124D
Concentration0.2 mg/mL
TargetCD33
ImmunogenRBL1 Transfected with full length mCD33
PurityThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD33, also known as Siglec-3, Sigle, gp67, p67, and gp6, is a member of the sialic acid-binding immunoglobulin lectins (Siglec). CD33 extracellular portion contains two immunoglobulin domains (one IgV and one IgC2 domain). The intracellular portion of CD33 contains immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that are implicated in inhibition of cellular activity. CD33 is primarily expressed on granulocytes in peripheral blood and spleen, as well as on myeloid precursors in the bone marrow.

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