APC anti-mouse CD64 FcgammaRI Antibody anti-CD64 - X54-5/7.1,BioLegend,139306
The X54-5/7.1 antibody reacts with mouse strains carrying CD64a and b alleles but not CD64d. X54-5/7.1 recognizes a conformational determinant formed between domains 2 and 3. Additional reported application (for relevant formats) include: immunoprecipitation1, and spatial biology (IBEX)5,6. Clone X54-5/7.1 is not found to be useful for Western blots1.
Host
Mouse
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB477316509
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameAPC anti-mouse CD64 FcgammaRI Antibody anti-CD64 - X54-5/7.1
Cat. No.139306
HostMouse
RRIDAB_11219205 (BioLegend Cat. No. 139305)AB_11219391 (BioLegend Cat. No. 139306)
IsotypeMouse IgG1, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberX54-5/7.1
Concentration0.2 mg/ml
TargetCD64
ImmunogenBALB/c mouse FcγRI-human IgG Fc fusion protein.
PurityThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcRI. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and mast cells. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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