APC anti-mouse DLL4 Antibody anti-Delta-like 4 - HMD4-1,BioLegend,130814
Host
Armenian Hamster
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB923492357
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameAPC anti-mouse DLL4 Antibody anti-Delta-like 4 - HMD4-1
Cat. No.130814
HostArmenian Hamster
RRIDAB_2246026 (BioLegend Cat. No. 130813)AB_2092982 (BioLegend Cat. No. 130814)
IsotypeArmenian Hamster IgG
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberHMD4-1
Concentration0.2 mg/ml
TargetDelta-like 4
ImmunogenCHO cells expressing murine DLL4
PurityThe antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only
Scientific Background
The Notch receptors and their ligands are highly conserved from invertebrates to mammals. Delta-like 4 (DLL4) is one of four or five Notch ligands identified. The binding to Notch receptor results in the proteolysis of Notch and movement of intracellular portions of Notch into the nucleus. This translocation triggers a series of signaling processes. DLL4 is reported to be essential for the regulation of angiogenesis. In thymus, DLL4 is an essential Notch1 ligand responsible for T cell lineage commitment.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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