APC anti-mouse IL-21R Antibody anti-IL-21R - 4A9,BioLegend,131910
Host
Rat
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB560110542
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAPC anti-mouse IL-21R Antibody anti-IL-21R - 4A9
Cat. No.131910
HostRat
RRIDAB_2295868 (BioLegend Cat. No. 131909)AB_2124133 (BioLegend Cat. No. 131910)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number4A9
Concentration0.2 mg/ml
TargetIL-21R
ImmunogenRat YB2/0 hybridoma transfectant cell line expressing truncated IL-21R
PurityThe antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
The IL-21R is a member of the cytokine receptor family that closely resembles IL-2R beta and IL-4R alpha. IL-21R is expressed by all mature lymphocytes and up-regulated after B and/or T cell activation, with the highest expression by activated B cells. A functional IL-21R consists of the IL-21R subunit and the commone gamma-chaiin. Upon binding to IL-21, it activates Jak-1, Jak-3, STAT1, STAT3 and STAT 5 transduction pathway.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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