APC anti-mouse Notch 4 Antibody anti-Notch 4 - HMN4-14,BioLegend,128413

Host

Armenian Hamster

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB361260978

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

BioLegend

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameAPC anti-mouse Notch 4 Antibody anti-Notch 4 - HMN4-14
Cat. No.128413
HostArmenian Hamster
RRIDAB_2151253 (BioLegend Cat. No. 128413)
IsotypeArmenian Hamster IgG
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberHMN4-14
Concentration0.2 mg/ml
TargetNotch 4
ImmunogenNotch4-Fc recombinant protein
PurityThe antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

The Notch receptors and their ligands are highly conserved from invertebrates to mammals.The Delta-like 1 (Dll1) is one of the four or five Notch ligands identified.The binding to Notch receptor results in the proteolysis of Notch and movement of intracellular portion of Notch into the nucleus.This translocation triggers a series of signaling process.Delta-like 1 is reported to be essential for the maintenance of marginal zone B cells in normal mice and engagement of Notch 1 by Dll 1 promotes differentiation of B lymphocytes to antibody-secreting cells.

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.