APC anti-mouse TCR β chain Recombinant Antibody, TCR β chain, QA18A18,BioLegend,159708

Clone QA18A18 of antibody can block binding of H57-597 clone on target and vice versa. The QA18A18 antibody can be used for T-cell activation. The QA18A18 antibody does not cross-react with γ/δ TCR-bearing T cells.

Host

Rat

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB394045234

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NameAPC anti-mouse TCR β chain Recombinant Antibody, TCR β chain, QA18A18
Cat. No.159708
HostRat
RRIDAB_2888831 (BioLegend Cat. No. 159707)AB_2888831 (BioLegend Cat. No. 159708)
IsotypeRat IgG1, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityRecombinant
Clone NumberQA18A18
Concentration0.2 mg/mL
TargetTCR beta chain
ImmunogenAffinity purified TCR from mouse DO-11.10 cells
PurityThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR-β is a member of the immunoglobulin superfamily and a component of the CD3/TCR complex (along with TCR-α). It is expressed on α/β TCR-bearing T cells and thymocytes. The CD3/TCR complex plays a key role in antigen recognition, signal transduction, and T cell activation.

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