APC anti-mouse Tim-4 antibody, Tim-4, RMT4-54,BioLegend,130021
Additional reported applications (for the relevant formats of this clone) include:in vivoinduction of auto-antibody production1and blockade of dendritic cell Tim-42.
Host
Rat
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB211798961
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAPC anti-mouse Tim-4 antibody, Tim-4, RMT4-54
Cat. No.130021
HostRat
RRIDAB_2892285 (BioLegend Cat. No. 130021)AB_2892285 (BioLegend Cat. No. 130022)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberRMT4-54
Concentration0.2 mg/mL
TargetTim-4
ImmunogenMouse TIM4-Ig fusion protein
PurityThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
Tim-4 is a transmembrane protein known as T cell immunoglobulin and mucin domain containing protein-4. It is expressed on antigen-presenting cells and not on T cells. Tim-4 binds to Tim-1 to promote T cell proliferation by enhancing cell division and reducing apoptosis. Tim-4 bind to phosphatidylserine through its FG-CC’ binding cleft in the N-terminal IgV domain to facilitate the clearance of apoptotic cells or bodies.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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