APC anti-mouse/human CD207 Langerin Antibody anti-CD207 - 4C7,BioLegend,144206
Host
Mouse
Reactivity
Mouse, Human
Application
FC - Quality tested
Platform ID
BAB561110062

BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAPC anti-mouse/human CD207 Langerin Antibody anti-CD207 - 4C7
Cat. No.144206
HostMouse
RRIDAB_2561997 (BioLegend Cat. No. 144205)AB_2561998 (BioLegend Cat. No. 144206)
IsotypeMouse IgG2a, κ
ReactivityMouse, Human
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number4C7
Concentration0.2 mg/ml
TargetCD207
ImmunogenLangerin extracellular domain-Fc fusion protein
PurityThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD207, also known as langerin, is a 40 kD single-pass type II transmembrane protein, member of the C-type lectin family. CD207 is expressed on the cell surface and Birbeck granules (BGs) of Langerhans cells, and subsets of thymic and splenic dendritic cells. Its ligands are mannose,n-acetylglucosamine, fucose, and sulfated glycans. Langerin is involved in the antigen processing pathway through capture and internalization of its ligands.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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