APC anti-mouse / rat CD29 Antibody anti-CD29 - HMβ1-1,BioLegend,102215
Additional reported applications (for the relevant formats) include: immunoprecipitation1, immunohistochemistry4of acetone-fixed frozen sections,in vitroblocking of the adhesion of mouse tumor cell lines to extracellular matrix proteins andin vitroinhibition of T cell proliferative responses1, andin vivoinhibition of neutrophil migration2. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 102235 and 102236).
Host
Armenian Hamster
Reactivity
Mouse, Rat
Application
FC - Quality tested
Platform ID
BAB424142045
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameAPC anti-mouse / rat CD29 Antibody anti-CD29 - HMβ1-1
Cat. No.102215
HostArmenian Hamster
RRIDAB_492834 (BioLegend Cat. No. 102215)AB_492833 (BioLegend Cat. No. 102216)
IsotypeArmenian Hamster IgG
ReactivityMouse, Rat
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberHMβ1-1
Concentration0.2 mg/ml
TargetCD29
ImmunogenPurified mouse VLA-4 (α4β1, CD49d/CD29)
PurityThe antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD29 is a 130 kD protein, also known as integrin β1, VLA-β chain, or GPIIa. It is a member of the integrin family, expressed broadly on leukocytes, endothelial cells, smooth muscle, and epithelial cells. In association with CD49a-f, CD29 forms the VLA-1 through VLA-6 complexes, respectively. It plays an important role in cell-cell or cell-matrix interaction. The HMß1-1 antibody reacts with both mouse and rat CD29. It is able to block cell adhesion and inhibit T cell proliferation.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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