APC anti-mouse/rat CD42d Antibody anti-CD42d - 1C2,BioLegend,148505
Additional reported applications (for relevant formats) include: immunoprecipitation1,3.
Host
Armenian Hamster
Reactivity
Mouse, Rat
Application
FC - Quality tested
Platform ID
BAB357574013
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAPC anti-mouse/rat CD42d Antibody anti-CD42d - 1C2
Cat. No.148505
HostArmenian Hamster
RRIDAB_2564601 (BioLegend Cat. No. 148505)AB_2564602 (BioLegend Cat. No. 148506)
IsotypeArmenian Hamster IgG
ReactivityMouse, Rat
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number1C2
Concentration0.2 mg/ml
TargetCD42d
ImmunogenMouse platelets
PurityThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD42d is an 83 kD surface glycoprotein that non-covalently associates with GPIb and GPIX to form a receptor complex for von Willebrand factor on megakaryocytes and resting platelets. Binding sites for von Willebrand factor and thrombin have been localized to the GPIba chain of the GPI-b-V-IX complex. Platelet activation with thrombin cleaves the GPI-b-V-IX complex to release a 69 kD soluble fragment. Presence of the GPI-b-V-IX complex is important in Bernard-Soulier syndrome, a rare bleeding disorder.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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