APC anti-rat CD43 Antibody anti-CD43 - W313,BioLegend,202814

Additional reported (for the relevant formats) applications include: immunohistochemical staining of acetone-fixed frozen sections1and paraffin-embedded sections4.

Host

Mouse

Reactivity

Rat

Application

FC -Quality tested

Platform ID

BAB663261006

BioLegend

Headquarters

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Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NameAPC anti-rat CD43 Antibody anti-CD43 - W313
Cat. No.202814
HostMouse
RRIDAB_2728224 (BioLegend Cat. No. 202814)
IsotypeMouse IgG1, κ
ReactivityRat
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone NumberW3/13
Concentration0.2 mg/ml
TargetCD43
ImmunogenRat thymocyte membrane glycoproteins
PurityThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD43, also known as Ly-48, Leukosialin, Sialophorin, Leukocyte Sialoglycoprotein, and W3/13, is a large single chain of type I transmembrane glycoprotein with abundant O-glycosylation and sialylation sites. It has been reported that CD43 binds to CD54 and Siglec-1. CD43 plays dual roles in cell adhesion and anti-adhesion, as well as costimulation of T cell activation and survival, and induction of apoptosis of T cells and hematopoietic progenitors.

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