APPL1 antibody, Internal,Genetex,GTX89127

Host

Goat

Reactivity

Human, Rat

Application

WB

Conjugate

Unconjugated

Platform ID

BAB648290724

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameAPPL1 antibody, Internal
Cat. No.GTX89127
Gene ID (Entrez)26060
HostGoat
IsotypeIgG
ReactivityHuman, Rat
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
Concentration0.50 mg/ml (Please refer to the vial label for the specific concentration.)
TargetAPPL1
ImmunogenPeptide with sequence C-NRYSRLSKKRENDK, from the internal region of the protein sequence according to NP_036228.1.
PurityPurified by ammonium sulphate precipitation followed by antigen affinity chromatography
Appearance/FormLiquid
FormulationTBS, 0.5% BSA,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]

Synonyms

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 , APPL , DIP13alpha , MODY14

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