ASBT antibody,Genetex,GTX51595

Host

Rabbit

Reactivity

Rat

Application

WB

Conjugate

Unconjugated

Platform ID

BAB244728205

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameASBT antibody
Cat. No.GTX51595
Gene ID (Entrez)6555
HostRabbit
IsotypeIgG
ReactivityRat
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetSLC10A2
ImmunogenKLH conjugated synthetic peptide derived from human ASBT(178-195).
PurityProtein A purified
Appearance/FormLiquid
Formulation1% BSA, 50% Glycerol,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). [provided by RefSeq, Mar 2010]

Synonyms

solute carrier family 10 member 2 , ASBT , IBAT , ISBT , NTCP2 , PBAM

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