ASCL1 antibody,Genetex,GTX37779

Host

Rabbit

Reactivity

Human

Application

IHC-P

Conjugate

Unconjugated

Platform ID

BAB334607571

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameASCL1 antibody
Cat. No.GTX37779
Gene ID (Entrez)429
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationIHC-P
ClonalityPolyclonal
Concentration0.5 mg/ml (Please refer to the vial label for the specific concentration.)
TargetASCL1
ImmunogenKLH conjugated synthetic peptide derived between 161-240 amino acids of human MASH1
PurityProtein A purified
Appearance/FormLiquid
Formulation10mM TBS, 0.5% BSA, 25% Glycerol,0.015% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq, Jul 2008]

Synonyms

achaete-scute family bHLH transcription factor 1 , ASH1 , HASH1 , MASH1 , bHLHa46

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