ASCL1 antibody,Genetex,GTX01090

Host

Goat

Reactivity

Mouse, Rat

Application

WB

Conjugate

Unconjugated

Platform ID

BAB965639703

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameASCL1 antibody
Cat. No.GTX01090
Gene ID (Entrez)429
HostGoat
IsotypeIgG
ReactivityMouse, Rat
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
Concentration0.5 mg/ml (Please refer to the vial label for the specific concentration.)
TargetASCL1
ImmunogenPeptide with sequence C-HKSAPKQVKRQRS, from the internal region of the protein sequence according to NP_004307.2.
PurityPurified by ammonium sulphate precipitation followed by antigen-affinity chromatographyFrom serum
Appearance/FormLiquid
FormulationTBS, 0.5% BSA,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq, Jul 2008]

Synonyms

ASCL1 , ASH1 , HASH1 , MASH1 , achaetescute family bHLH transcription factor 1 , bHLHa46

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