ASK1 Recombinant Antibody, APC Conjugated,Bioss,bsm-61166r-apc-100ul

Host

Rabbit

Reactivity

Human, Mouse

Application

WB, FCM, IF(IHC-P), IF(ICC)

Conjugate

APC

Platform ID

BAB236629335

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameASK1 Recombinant Antibody, APC Conjugated
Cat. No.bsm-61166r-apc-100ul
Accession NumberQ99683
Gene ID (Entrez)4217
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ConjugationAPC
ApplicationWB, FCM, IF(IHC-P), IF(ICC)
Working DilutionsWB:1:500-2000 | FCM:FCM1:50-100 | IF(IHC-P):IFIHC-P1:50-200 | IF(ICC):IFICC1:50-200
ClonalityRecombinant
ConcentrationLot dependent
PurityPurified by Protein A.
FormulationAqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageStore at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Scientific Background

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signaling for determination of cell fate such as differentiation and survival. Plays a crucial role in the apoptosis signal transduction pathway through mitochondria-dependent caspase activation. MAP3K5/ASK1 is required for the innate immune response, which is essential for host defense against a wide range of pathogens.

Synonyms

Apoptosis signal- regulating kinase 1;ASK-1;MAP3K5;ASK1;MAPKKK5; MEK kinase 5;MEKK5.

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