ATP-Citrate Synthase (ACLY) Antibody,Abbexa,abx010428

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis.

Host

Mouse

Reactivity

Human, Mouse, Monkey, Rat

Application

ELISA, WB, IHC, IF/ICC, FCM

Conjugate

Unconjugated

Platform ID

BAB111828580

Abbexa

Headquarters

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

Contact

Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951

Product Specifications

Specifications

NameATP-Citrate Synthase (ACLY) Antibody
Cat. No.abx010428
Accession NumberP53396
Gene ID (Entrez)47
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse, Monkey, Rat
ConjugationUnconjugated
ApplicationELISA, WB, IHC, IF/ICC, FCM
Working DilutionsELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/50, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
ClonalityMonoclonal
Concentration1 mg/ml
Molecular Weight125 kDa
ImmunogenPurified recombinant fragment of human ACLY (AA: 306-502) expressed in E. coli.
PurityPurified from ascites by Protein G chromatography.
Appearance/FormLiquid
FormulationPBS, containing 0.05% sodium azide.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only

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