ATP-Dependent Translocase ABCB1 (ABCB1) Antibody,Abbexa,abx149070

ATP-Dependent Translocase ABCB1 (ABCB1) Antibody is a Rabbit Polyclonal antibody for the detection of P Glycoprotein. ABCB1 (also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer.

Host

Rabbit

Reactivity

Human, Mouse

Application

ELISA, WB, IHC, IP

Conjugate

Unconjugated

Platform ID

BAB940775552

Abbexa

Headquarters

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

Contact

Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951

Product Specifications

Specifications

NameATP-Dependent Translocase ABCB1 (ABCB1) Antibody
Cat. No.abx149070
Accession NumberP08183
Gene ID (Entrez)5243
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationELISA, WB, IHC, IP
Working DilutionsWB: 1/200 - 1/1000, IHC: 1/50 - 1/500, IP: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Concentration2 mg/ml
Molecular WeightObserved MW: 142 kDa
TargetABCB1
ImmunogenABCB1
PurityPurified by immunogen affinity chromatography.
Appearance/FormLiquid
FormulationPBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only

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