ATPB Antibody (YA6197),MedChemexpress,HY-P86505

ATPB is the catalytic subunit beta of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V), which produces ATP from ADP in the presence of a proton gradient across the membrane generated by electron transport complexes of the respiratory chain (Probable). The ATP synthase complex consists of a soluble F(1) head domain (the catalytic core) and a membrane F(1) domain (the membrane proton channel), linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk (PubMed:37244256). During catalysis, ATP synthesis in the F(1) catalytic domain is coupled to proton translocation via a rotary mechanism of the central stalk subunits (Probable). In vivo, ATPB can only synthesize ATP, although its ATP hydrolase activity can be activated artificially in vitro (By similarity). Together with the subunit alpha (ATP5F1A), it forms the catalytic core in the F(1) domain (PubMed:37244256).