AXL antibody [GT1174],Genetex,GTX635210

Host

Mouse

Reactivity

Human, Mouse

Application

WB

Conjugate

Unconjugated

Platform ID

BAB396477859

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameAXL antibody [GT1174]
Cat. No.GTX635210
Gene ID (Entrez)558
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB
ClonalityMonoclonal
Concentration1.54 mg/ml (Please refer to the vial label for the specific concentration.)
TargetAXL
ImmunogenRecombinant protein encompassing a sequence within the Extracellular domain of human AXL. The exact sequence is proprietary.
PurityAffinity purified by Protein G.
Appearance/FormLiquid
FormulationPBS, 20% Glycerol,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]

Synonyms

AXL receptor tyrosine kinase , ARK , JTK11 , Tyro7 , UFO

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