Acetyl-Histone H4-K12 Rabbit mAb- ABclonal,ABclonal,A22754

Reactivity

Human, Mouse, Rat, Other (Wide Range Predicted)

Application

WB, DB, IHC-P, ELISA, ChIP, ChIP-seq

Conjugate

Unconjugated

Platform ID

BAB157602459

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

Tel:
Fax:

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameAcetyl-Histone H4-K12 Rabbit mAb- ABclonal
Cat. No.A22754
Accession NumberP62805
Gene ID (Entrez)8359
IsotypeIgG
ReactivityHuman, Mouse, Rat, Other (Wide Range Predicted)
ConjugationUnconjugated
ApplicationWB, DB, IHC-P, ELISA, ChIP, ChIP-seq
Working DilutionsWB:1:500 - 1:1000 | DB:1:500 - 1:1000 | IHC-P:1:100 - 1:500 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. | ChIP:5μg antibody for 5μg-10μg of Chromatin | ChIP-seq:1:50 - 1:200
Clone NumberARC56881
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.

Synonyms

H4; H4/n; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4F2; H4FN; FO108; H4-16; H4C11; H4C12; H4C13; H4C15; H4C16; HIST2H4; HIST2H4A; Acetyl-Histone H4-K12

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