Acetyl-Histone H4-K12 Rabbit mAb- ABclonal,ABclonal,A23683

Reactivity

Human, Mouse, Rat, Other (Wide Range Predicted)

Application

WB, IP, IHC-P, ChIP, ELISA

Conjugate

Unconjugated

Platform ID

BAB283064737

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Fax:

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameAcetyl-Histone H4-K12 Rabbit mAb- ABclonal
Cat. No.A23683
Accession NumberP62805
Gene ID (Entrez)8359
IsotypeIgG
ReactivityHuman, Mouse, Rat, Other (Wide Range Predicted)
ConjugationUnconjugated
ApplicationWB, IP, IHC-P, ChIP, ELISA
Working DilutionsWB:1:1000 - 1:3000 | IHC-P:1:500 - 1:1000 | IP:0.5μg-4μg antibody for 200μg-400μg extracts of whole cells | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. | ChIP:5μg antibody for 5μg-10μg of Chromatin
Clone NumberARC57733
Molecular Weight11 kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Synonyms

H4/I; H4C1; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4FI; H4-16; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; HIST1H4B; Acetyl-Histone H4-K12

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