α-Actin-1 (ACTA1) Rabbit mAb,ABclonal,A2280

Reactivity

Human, Mouse, Rat

Application

WB, IF-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB104816544

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Nameα-Actin-1 (ACTA1) Rabbit mAb
Cat. No.A2280
Accession NumberP68133
Gene ID (Entrez)58
RRIDAB_2862988
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IF-P, ELISA
Working DilutionsWB:1:1000 - 1:5000 | IF-P:1:50 - 1:200 | ELISA:Recommended starting concentration is 1 μg/mL.
Clone NumberARC1914
Molecular Weight42kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause a variety of myopathies, including nemaline myopathy, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects with manifestations such as hypotonia.

Synonyms

ACTA; ASMA; CFTD; MPFD; NEM1; NEM2; NEM3; SHPM; CFTD1; CFTDM; CMYP2A; CMYP2B; CMYP2C; α-Actin-1 (ACTA1)

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