Activin Receptor Type IB antibody [11A7],Genetex,GTX52505

Host

Mouse

Reactivity

Human

Application

WB IHC-P

Conjugate

Unconjugated

Platform ID

BAB933721238

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameActivin Receptor Type IB antibody [11A7]
Cat. No.GTX52505
Gene ID (Entrez)91
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IHC-P
ClonalityMonoclonal
Concentration200 μg/ml (Please refer to the vial label for the specific concentration.)
TargetACVR1B
ImmunogenRecombinant hu-ALK4 extra cellular domain
PurityProtein G purifiedFrom tissue culture supernatant
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]

Synonyms

ACTRIB , ACVR1B , ACVRLK4 , ALK4 , SKR2 , activin A receptor type 1B , Activin A receptor type IB

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