Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) Antibody,Abbexa,abx001175
ACSL5 Antibody is a Rabbit Polyclonal antibody against ACSL5. Acyl-CoA synthetase 5, a member of the ACSL gene family that catalyzes the activation of long-chain fatty acids for lipid biosynthesis, is the only ACSL isoform that is both, located on mitochondria and functionally involved in enterocyte apoptosis.ACSL5 could play a role in promoting fatty acid-induced lipoapoptosis in hepatocytes as important mechanism in fatty liver-related disorders(PMID:20470896). ACSL5 is most abundant in liver, brown adipose tissue, and intestine and is located on both the mitochondrial membrane and endoplasmic reticulum(PMID:20798351). It has 3 isoforms produced by alternative splicing. This antibody is specific to ACSL5.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Application
ELISA, WB
Conjugate
Unconjugated
Platform ID
BAB115070701
Abbexa
Contact
Tel: +44 (0) 1223 755950
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Product Specifications
Specifications
NameAcyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) Antibody
Cat. No.abx001175
Accession NumberQ9ULC5
Gene ID (Entrez)51703
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationELISA, WB
Working DilutionsELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Concentration> 0.2 mg/ml
Molecular WeightCalculated MW: 76 kDa Observed MW: 70-76 kDa
TargetACSL5
ImmunogenRecombinant protein corresponding to ACSL5. The exact sequence is proprietary.
PurityPurified by affinity chromatography.
Appearance/FormLiquid
FormulationPBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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