Ado-Trastuzumab Emtansine Biosimilar - Research Grade,ichor.bio,ICH4014

Detects human HER2. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Ado-trastuzumab emtansine.

Host

Humanized

Reactivity

Human

Platform ID

BAB007827948

ichor.bio

Headquarters

Grove Business Park Downsview Road Wantage OX12 9FF

Contact

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Product Specifications
Scientific Background
Synonyms

Specifications

NameAdo-Trastuzumab Emtansine Biosimilar - Research Grade
Cat. No.ICH4014
Accession NumberP04626
HostHumanized
IsotypeHuman IgG1
ReactivityHuman
Concentration1.0 - 5.0 mg/ml
TargetHER2
Purity>95% by SDS-PAGE and HPLC
Endotoxin Level≤ 1.0 EU/mg as determined by the LAL method
ShippingBlue ice
FormulationICH3001-100ml ICH3002-100ml ICH3003-100ml
StorageStable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Regulatory StatusFor research use only

Scientific Background

Ado-trastuzumab emtansine is a HER2-targeted antibody-drug conjugate which contains the humanized anti-HER2 IgG1, trastuzumab, covalently linked to the microtubule inhibitory drug DM1 via the stable thioether linker MCC. Trastuzumab is produced by Chinese

Synonyms

Receptor tyrosine-protein kinase erbB-2, MLN 19, HER2, HER2/neu

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