Alexa Fluor® 488 Anti-CD72 antibody [3F3],Abcam,AB288659
Host
Mouse
Reactivity
Human
Application
Flow Cyt
Conjugate
Alexa Fluor® 488
Platform ID
BAB215552101
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAlexa Fluor® 488 Anti-CD72 antibody [3F3]
Cat. No.AB288659
HostMouse
IsotypeIgG2b
ReactivityHuman
ConjugationAlexa Fluor® 488
ApplicationFlow Cyt
ClonalityMonoclonal
Clone Number3F3
ImmunogenCell preparation containing CD72 protein. The exact immunogen used to generate this antibody is proprietary information.
PuritySize-exclusion chromatography
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.098% Sodium azide Constituents: PBS, 0.2% BSA
Storage+4°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Co-receptor of B cell receptor (BCR) that plays both positive and negative roles on B-cell functions. Recognizes the Sm/ribonucleoprotein (RNP) self-antigen ligand, and coligation of CD72 and BCR inhibits BCR signaling. Mechanistically, ligand binding leads to the recruitment of PTPN6/SHP-1 to the BCR complex which is inhibitory to BCR signaling. Also acts as a ligand for CD5 and thereby plays a critical role in maintaining regulatory T and B-cell homeostasis. See full target information CD72
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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