Alexa Fluor® 488 Anti-CNPase antibody [11-5B],Abcam,AB313960

What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Mouse

Reactivity

Human, Mouse, Human

Application

ICC/IF, IHC-P

Conjugate

Alexa Fluor® 488

Platform ID

BAB966126825

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAlexa Fluor® 488 Anti-CNPase antibody [11-5B]
Cat. No.AB313960
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse, Human
ConjugationAlexa Fluor® 488
ApplicationICC/IF, IHC-P
ClonalityMonoclonal
Clone Number11-5B
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 30% Glycerol (glycerin, glycerine), 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Myelin-associated enzyme that catalyzes the phosphodiester hydrolysis of 2',3'-cyclic nucleotides to 2'-nucleotides. In the mitochondria, regulates the functioning of the mitochondrial permeability transition pore (mPTP), and thus is involved in the mechanisms of cell death, both apoptosis and necrosis. Acts as an antiviral factor by suppressing the assembly of SARS-CoV-2 virions (PubMed : 38117830).. Acts as an antiviral factor by suppressing the assembly of HIV-1 virions through direct interaction with GAG. See full target information CNP

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