Alexa Fluor® 488 Anti-DNAJB6 antibody [EPR17122] - N-terminal,Abcam,AB322167
Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Alexa Fluor® is a registered trademark of Molecular Probes, Inc, a Thermo Fisher Scientific Company. The Alexa Fluor® dye included in this product is provided under an intellectual property license from Life Technologies Corporation. As this product contains the Alexa Fluor® dye, the purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). As this product contains the Alexa Fluor® dye the sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: in manufacturing; (ii) to provide a service, information, or data in return for payment (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are sold for use in research. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or [email protected].
Host
Rabbit
Reactivity
Human, Mouse, Human, Mouse, Rat
Application
Flow Cyt (Intra), ICC/IF, IHC-P
Conjugate
Alexa Fluor® 488
Platform ID
BAB154370218

Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70 (PubMed : 10954706, PubMed : 28233300). Plays an indispensable role in the organization of KRT8/KRT18 filaments (PubMed : 10954706). Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin (PubMed : 11896048, PubMed : 22366786). Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins (PubMed : 20159555, PubMed : 22366786). Also reduces cellular toxicity and caspase-3 activity (PubMed : 11896048).. Isoform B. Isoform B but not isoform A inhibits huntingtin aggregation. See full target information DNAJB6
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
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