Alexa Fluor® 488 Anti-Histone H3 (di methyl K4) antibody [Y47],Abcam,AB200024

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents .

Host

Rabbit

Reactivity

Human, Human, Mouse, Rat

Application

Flow Cyt (Intra), ICC/IF, IHC-P

Conjugate

Alexa Fluor® 488

Platform ID

BAB343513179

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAlexa Fluor® 488 Anti-Histone H3 (di methyl K4) antibody [Y47]
Cat. No.AB200024
HostRabbit
IsotypeIgG
ReactivityHuman, Human, Mouse, Rat
ConjugationAlexa Fluor® 488
ApplicationFlow Cyt (Intra), ICC/IF, IHC-P
ClonalityMonoclonal
Clone NumberY47
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 30% Glycerol (glycerin, glycerine), 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. See full target information H3C1 di methyl K4

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