Alexa Fluor® 488 Anti-TMEM119 antibody [106-6] - Microglial marker,Abcam,AB225497
What is this antibody validated in? Alexa Fluor® 488 Anti-TMEM119 antibody [106-6] (ab225497) is a rabbit recombinant monoclonal antibody and is validated for use in Flow Cytometry (Intra), Flow Cytometry (Flow Cyt) in Human, Mouse samples. Related products Antibody clone 106-6 is also available pre-conjugated to a variety of labels for your convenience – Anti-TMEM119 Alexa Fluor® 488 [106-6] (ab225497). Specificity confirmed The specificity of Alexa Fluor® 488 Anti-TMEM119 antibody [106-6] (ab225497) has been confirmed by Flow Cytometry (Intracellular) testing in Tmem119 Knockout Mouse CD11b+ cells samples. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Human, Human, Mouse
Application
Flow Cyt (Intra), ICC/IF, Flow Cyt
Conjugate
Alexa Fluor® 488
Platform ID
BAB724197949

Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Plays an important role in bone formation and normal bone mineralization (PubMed : 20025746, PubMed : 22416756, PubMed : 26207632). Promotes the differentiation of myoblasts into osteoblasts (PubMed : 20025746, PubMed : 22416756, PubMed : 22579779). May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway (PubMed : 21239498, PubMed : 22579779). Up-regulates the expression of ATF4 which plays a central role in osteoblast differentiation (PubMed : 24362451). Essential for normal spermatogenesis and late testicular differentiation (PubMed : 26207632). See full target information Tmem119
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
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