Alexa Fluor 488 anti-Nanog Antibody anti-Nanog - 23D2-3C6,BioLegend,674006

This clone is not recommended for ChIP (Chromatin Immunoprecipitation) assays (as determined by in-house testing).

Host

Mouse

Reactivity

Human

Application

ICC -Quality tested

Platform ID

BAB110247729

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameAlexa Fluor 488 anti-Nanog Antibody anti-Nanog - 23D2-3C6
Cat. No.674006
HostMouse
RRIDAB_2571952 (BioLegend Cat. No. 674006)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationICC -Quality tested
ClonalityMonoclonal
Clone Number23D2-3C6
Concentration0.5 mg/ml
TargetNanog
ImmunogenFull length human recombinant protein expressed in bacteria
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

Nanog is a transcription factor that plays key roles in the maintenance of pluripotency and self-renewal in embryonic stem cells. Nanog expression is regulated by other transcription factors, which include Sox2 and Oct-4. It also plays a role in epithelial malignancy and is enriched in cancer stem cells. The ablation of nanog is sufficient to reduce the cancer stem cell pool.

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