Alexa Fluor 488 anti-human CD27 Recombinant Antibody anti-CD27 - QA17A18,BioLegend,393204
Clone QA17A18 does not block clones 0323, M-T271, or LG.3A10, indicating a unique epitope.
Host
Mouse
Reactivity
Human
Application
FC -Quality tested
Platform ID
BAB687649294
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameAlexa Fluor 488 anti-human CD27 Recombinant Antibody anti-CD27 - QA17A18
Cat. No.393204
HostMouse
RRIDAB_2750088 (BioLegend Cat. No. 393203)AB_2750089 (BioLegend Cat. No. 393204)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC -Quality tested
ClonalityRecombinant
Clone NumberQA17A18
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD27
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70, and plays a role in costimulation of T cell activation and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-κB and SAPK/JNK activation.
Category Paths
- Products>Primary Antibodies>Recombinant Antibodies
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