Alexa Fluor 488 anti-human CD335 NKp46 Antibody anti-CD335 - 9E2,BioLegend,331938
Clone 9E2 has been shown to block NK activation through NKp46.6
Host
Mouse
Reactivity
Human
Application
FC -Quality tested
Platform ID
BAB762846975
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAlexa Fluor 488 anti-human CD335 NKp46 Antibody anti-CD335 - 9E2
Cat. No.331938
HostMouse
RRIDAB_2715915 (BioLegend Cat. No. 331937)AB_2715916 (BioLegend Cat. No. 331938)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone Number900
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD335
ImmunogenNKp46-Fc fusion protein
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD335, also known as NKp46, is a member of the natural cytotoxicity receptor (NCR) family which triggers cytotoxicity in NK cells. CD335 is directly involved in target cell recognition and lysis, and is exclusively expressed on CD3-CD56+NK cells, suggesting it is a universal marker for NK cells. NKp46, along with NKp30 and NKp44, is referred to as a natural cytoxicity receptor (NCR) and plays a very important role in killing virus-infected tumor cells and MHC-class I-unprotected cells.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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