Alexa Fluor 488 anti-mouse CD16-2 FcgammaRIV Antibody anti-CD16-2 - 9E9,BioLegend,149523
Additional reported applications (for the relevant formats of this clone) include: blocking of Fc?RIV function1and inhibition of immune complex binding1,2. The LEAF™ or Ultra-LEAF™ purified antibody (Endotoxin < EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (contact our custom solutions team).
Host
Armenian Hamster
Reactivity
Mouse
Application
FC -Quality tested
Platform ID
BAB388159325
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameAlexa Fluor 488 anti-mouse CD16-2 FcgammaRIV Antibody anti-CD16-2 - 9E9
Cat. No.149523
HostArmenian Hamster
RRIDAB_2687087 (BioLegend Cat. No. 149523)AB_2687088 (BioLegend Cat. No. 149524)
IsotypeArmenian Hamster IgG
ReactivityMouse
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone Number9000000000
Concentration0.5 mg/ml
TargetCD16.2
ImmunogenFCγR4 —EC domain fusion with IgG1 Fc
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
FcγRIV, also known as CD16.2, is an intermediate-affinity activating receptor for IgG2a and IgG2b. CD16.2 is the mouse homolog of human FcγRIIIA. CD16.2 is a low-affinity IgE receptor for all allotypes and the ligation of FcγRIV by antigen-IgE immune complexes promotes macrophage-mediated phagocytosis and is involved in lung inflammation.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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