Alexa Fluor 488 anti-mouse CD48 Antibody anti-CD48 - HM48-1,BioLegend,103414

The HM48-1 antibody is useful for blockingin vitroandin vivoCD48 mediated interactions. Additional reported applications (for the relevant formats) include: immunoprecipitation1, costimulation of T cell proliferation1,2, blocking of CD48-CD2 interaction1, and inhibition of CTL activity and graft rejection1,2. Forin vivostudies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. Nos. 103452-103456) with a lower endotoxin limit (Endotoxin < 0.01 EU/µg).

Host

Armenian Hamster

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB610586302

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NameAlexa Fluor 488 anti-mouse CD48 Antibody anti-CD48 - HM48-1
Cat. No.103414
HostArmenian Hamster
RRIDAB_571979 (BioLegend Cat. No. 103414)
IsotypeArmenian Hamster IgG
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberHM48-1
Concentration0.5 mg/ml
TargetCD48
ImmunogenMouse T lymphoma MBL-2
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD48 is a 45 kD GPI-anchored glycoprotein also known as BCM1, Blast-1 (human), and OX-45 (rat). It is a member of the Ig superfamily, expressed on T and B cells and monocytes/macrophages. It plays a role in adhesion and T cell recognition. The primary ligands for CD48 are CD2 and CD244.

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